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But I came away from those conversations with a clearer view of where my responsibility actually sits, which is between what the science says and what we put our customers names on
Patients needing more aggressive weight reduction (20%+ body weight loss) are likely better served by tirzepatide or future triple-agonist therapies like retatrutide that produce higher average weight loss
Relatedly, before RYGB, a GLP-1 antagonist led to an increase in basal network connectivity and a decrease in functional connectivity in the frontoparietal network in patients with obesity (van Duinkerken et al., 2021)
The allure of quick fixes and performance enhancements can blind you to the irreversible damage these unapproved peptides can cause
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